Search results for "Sodium metabisulfite"

showing 4 items of 4 documents

Modelling the effect of ascorbic acid, sodium metabisulphite and sodium chloride on the kinetic responses of lactic acid bacteria and yeasts in table…

2010

he goal of this work was to apply the Quasi-chemical primary model (a system of four ordinary differential equations that derives from a hypothetical four-step chemical mechanism involving an antagonistic metabolite) in the study of the evolution of yeast and lactic acid bacteria populations during the storage of Manzanilla–Aloreña table olives subjected to different mixtures of ascorbic acid, sodium metabisulphite and NaCl. Firstly, the Quasi-chemical model was applied to microbial count data to estimate the growth–decay biological parameters. The model accurately described the evolution of both populations during storage, providing detailed information on the microbial behaviour. Secondly…

Food HandlingTable oliveSodiumColony Count MicrobialQuasi-chemical modelchemistry.chemical_elementAscorbic AcidSodium ChlorideModels BiologicalMicrobiologychemistry.chemical_compoundOleaYeastsLactic acid bacteriaSulfitesPrimary modellingFood sciencebiologyFood preservationGeneral MedicineSodium metabisulfiteLactobacillaceaebiology.organism_classificationAscorbic acidYeastLactic acidchemistryBiochemistryLactobacillaceaeFruitFermentationFood MicrobiologyFermentationFood ScienceInternational Journal of Food Microbiology
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Sodium metabisulfite as a cytotoxic food additive induces apoptosis in HFFF2 cells

2021

Sodium metabisulfite (SMB), an antioxidant agent, is extensively used as a preservative in food industry. The current study was aimed to clarify its potential toxic effects on human fetal foreskin fibroblasts (HFFF2) cells, in vitro. Subsequently, MTT results illustrated that exposure to SMB significantly (p  0.0001) decreased HFFF2 cell viability in a dose-dependent manner, and the concentration of 25 μM reduced cell survival rates to 50% as the half-maximal inhibitory concentration of SMB. It was further shown that SMB exerted this cytotoxic effect on HFFF2 cells through apoptosis induction. qRT-PCR and western blotting results showed that treatment of HFFF2 cells with this food additive …

MalePreservativeAntioxidantfood.ingredientCell Survivalmedicine.medical_treatmentForeskinApoptosisPharmacology01 natural sciencesAnalytical Chemistrychemistry.chemical_compound0404 agricultural biotechnologyfoodAutophagymedicineHumansSulfitesCytotoxic T cellCytotoxicityCells Culturedbcl-2-Associated X ProteinCaspase 8Dose-Response Relationship DrugCaspase 3Food additive010401 analytical chemistry04 agricultural and veterinary sciencesGeneral MedicineSodium metabisulfiteFibroblasts040401 food scienceCaspase 9In vitro0104 chemical sciencesGene Expression RegulationchemistryApoptosisFood AdditivesReactive Oxygen SpeciesFood ScienceFood Chemistry
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Gas chromatographic evaluation of pesticide residue contents in nectarines after non-toxic washing treatments

2004

Washing with aqueous solutions of citric acid, ethanol, glycerol, hydrogen peroxide, potassium permanganate, sodium metabisulfite, sodium laurylsulfate (SLS), sodium hypochlorite, and urea is evaluated for pesticide residue reduction in nectarines and compared with simple tap water washing. Residues of pesticides commonly utilized in nectarines (chlorpyrifos, fenarimol, iprodione, malathion, methidathion, myclobutanil, parathion and pirimicarb) are extracted with ethyl acetate and anhydrous sodium sulfate, extract is concentred and analyzed by GC with nitrogen-phosphorus detection. The formation of possible toxic by-products (chlorpyrifos oxon, malaoxon, methidaoxon and paraoxon methyl) is …

Organophosphorus compoundsGCWashingChromatographyPesticide residuesPesticide residueSodiumOrganic ChemistryPesticide residues; Organophosphorus compounds; Fruits; Nectarines; Oxidative treatments; By-products; GC; WashingBy-productschemistry.chemical_elementOxidative treatmentsSodium metabisulfiteGeneral MedicineBiochemistryFruitsAnalytical Chemistrychemistry.chemical_compoundPotassium permanganatechemistryTap waterSodium hypochloriteNectarinesSodium sulfateHydrogen peroxideJournal of Chromatography A
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Physicochemical compatibility of mixtures of dornase alfa and tobramycin containing nebulizer solutions

2008

Patients suffering from cystic fibrosis (CF) often need to inhale multiple doses of different nebulizable drugs per day. Patients attempt to shorten the time consuming administration procedure by mixing drug solutions/suspensions for simultaneous inhalation. The objective of this experimental study was to determine whether mixtures of the nebulizer solution dornase alfa (Pulmozyme) with tobramycin nebulizer solutions (TOBI and GERNEBCIN 80 mg) are physico-chemically compatible. Drug combinations were prepared by mixing the content of one respule Pulmozyme with either one respule TOBI or one ampoule GERNEBCIN 80 mg. Test solutions were stored at room temperature and exposed to light. Dornase…

Pulmonary and Respiratory MedicineChemical PhenomenaCystic FibrosisExcipientAmpouleDrug Incompatibilitychemistry.chemical_compoundAdministration InhalationTobramycinDeoxyribonuclease IHumansMedicinePotencyChromatographyInhalationbusiness.industryNebulizers and VaporizersDornase alfaSodium metabisulfiteAnti-Bacterial AgentsDrug CombinationsPharmaceutical SolutionsNebulizerchemistryAnesthesiaPediatrics Perinatology and Child HealthTobramycinbusinessmedicine.drugPediatric Pulmonology
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